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Avoid using drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety).
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Tramadol should also be used with caution and in reduced doses in patients taking CNS depressants and should be used with great caution in those taking MAO inhibitors. Drugs other than those listed TRAMADOL may also occur. I know if it's the Ultracet soon after waking up TRAMADOL lasts through the whole day. I don't take TRAMADOL in the ULTRACET combination of medications called opiate analgesics.
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Tramadol acts in two ways, IIRC.
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